1. Some of the ways how SARS Cov2 is affecting us as Long COVID (LC):
- Immune dysregulation
- Auto immune disease
- micro clots
- viral debris
- persistence of SARS virus
- Viral reactivation- e.g. EBV, CMV
- end organ damage
It is one of the worst viruses to impact us. Stay safe
Do remember that it continues to debilitate us in many different ways, causing chronic illnesses.
Some will understand it now, some in a few years and a few perhaps never.
Meanwhile, SARS will continue its 'impact' ☹️
Long Covid risks in kids are worrisome.
Living with the virus shud mean by taking apt precautions timely & scientifically.
Covid-19 experts say they warned White House about chance of an Omicron-level event within the next two years | CNN
In March, the White House reached out to about a dozen Covid-19 experts who are closely following the evolution of the coronavirus to ask a simple question: What did they think were the chances of the world seeing a highly mutated variant, akin to Omicron, within the next two years?
Can someone convey this to the virus too please, that it's time to stop killing people and stop making them sick for months/years? And also pls stop new variants. Thanks.
RSV vaccine has been approved.
RSV kills 6k- 10k over 65 annually.
94% effective in reducing serious illness & 82.6% in reducing symptomatic infection in 60+ .
It has been a long wait for this one.
Hopefully a diagnostic test will solve this soon.
Younger males, severe disease were worse off.
Clearly COVID is adding to our health care burden both at individual and population level.
Spike-specific CD8+ activation correlates with the viral clearance
SARS-CoV-2 breakthrough infection induces rapid memory and de novo T cell responses: Immunity
Our understanding of T cell responses to SARS-CoV-2 vaccination and breakthrough infection has lagged behind B cells and antibodies. Here, Koutsakos et al. utilize longitudinal sampling to demonstrate a rapid activation of SARS-CoV-2-specific CD4+ and CD8+ T cells during breakthrough ..
A thread. 1/n
Cardiovascular disease and mortality sequelae of COVID-19 in the UK Biobank | Heart
Objective To examine association of COVID-19 with incident cardiovascular events in 17 871 UK Biobank cases between March 2020 and 2021. Methods COVID-19 cases were defined using health record linkage. Each case was propensity score-matched to two uninfected controls on age, sex, deprivation, body ..
Exercise. Just that.
A study highlights the delay in dementia by over 9 years, studied over 44 years in 1462 women aged 38 to 60.
Get up n move (if u can)
Midlife cardiovascular fitness and dementia | Neurology
Objective To investigate whether greater cardiovascular fitness in midlife is associated with decreased dementia risk in women followed up for 44 years. Methods A population-based sample of 1,462 women 38 to 60 years of age was examined in 1968. Of these, a systematic subsample comprising 191 women..
This Scotland wide longer term study shows hope for some and concerns for other symptoms in the longer term
This virus has changed us forever (in case you had missed that observation).
Long-Term Consequences of Asymptomatic SARS-CoV-2 Infection: A Systematic Review and Meta-Analysis - PMC
Little is known about the long-term consequences of asymptomatic infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We aimed to review the data available to explore the long-term consequences of asymptomatic SARS-CoV-2 infection ...
Anecdotally, kids with covid r getting sticky eyes more commonly.
Cases rising sharply in India. No mitigations. Fingers crossed.
COVID impact in pregnancy (neglected topic).
Various strains have varying negative impacts on both mother & foetus/infant.
Delta was perhaps the worst.
Please continue precautions, vaccinations & genomic sequencing.
Shutting eyes is the laziest thing one can do to evidence.
Dismantling the anti-vaxx industry | Nature Medicine
Investigations show that those spreading misinformation that undermines the rollout of vaccines against COVID-19 are well financed, determined and disciplined. To counter their activities, we need to understand them as an industry actively working to sow doubts about the deadliness of COVID-19, vacc..
SARS-CoV-2 infection damages the CD8+ T cell response in unvaccinated (reduced immune response to spike proteins)
Vaccinations- robust response.
Unvaccinated? think again!
Why are they still testing, recording, spreading fear? Stop testing like the rest? 😡😡
SARS Cov2 cont to cause serious issues in millions. Just saying.
Anti vaxxers, twist this, don’t open ur eyes to evidence & carry on endangering human lives by spreading wrong info.
Many many still suffer from pain, reduced quality of life, worsened finances, further risks ...
Be mindful, be kind. Stay updated, stay protected.
Only if govts cud b more scientific!
Hopefully more nuanced and better targeted approach prevails.
Dear elite athletes, athletes and everyone :),
If there are two things you can do to keep good health and increase performance, please ensure great sleep and well-maintained oral health (often neglected)
It will work wonders.