In response to Robin.
Covid is one the worst diseases around. Next few years will unravel further its impact. Hopefully research shall catch up and provide us better sollutions regarding covid than what we have now.
07:16 PM - Aug 25, 2023
In response to Anton Brakhage.
Thats always a huge issue. Undoubtedly Universal Healthcare should be the answer to cost worrries.
07:50 PM - Aug 05, 2023
In response to Christine.
sorry to hear that. This drug is a hope, but yet to go through human trials. So far so good though. research is painfully slow otherwise :( .
07:49 PM - Aug 05, 2023
In response to Anton Brakhage.
I really hope that kids question grown ups as and when they can, as why aren't they protected appropriately when science says how to.
04:49 AM - Apr 17, 2023
In response to Aviral Vatsa.
Further research is needed to fully understand the long-term effects of COVID-19 on cardiovascular health.
This study provides an important starting point for healthcare professionals to better understand and manage the cardiovascular risks associated with COVID-19.
END.
This study provides an important starting point for healthcare professionals to better understand and manage the cardiovascular risks associated with COVID-19.
END.
12:23 PM - Apr 10, 2023
In response to Aviral Vatsa.
It is important to monitor and manage cardiovascular risk factors in individuals with COVID-19, particularly in those who were hospitalized.
8/n
8/n
12:23 PM - Apr 10, 2023
In response to Aviral Vatsa.
Overall, individuals hospitalized with COVID-19 have an increased risk of incident cardiovascular events across a range of disease and mortality outcomes. The risk of most events is highest in the early post-infection period.
7/n
7/n
12:23 PM - Apr 10, 2023
In response to Aviral Vatsa.
Individuals not requiring hospitalization had an increased risk of VTE, but not of other cardiovascular-specific outcomes.
6/n
6/n
12:22 PM - Apr 10, 2023
In response to Aviral Vatsa.
Those hospitalized with COVID-19 as a secondary diagnosis had similarly increased cardiovascular risk. The associated risks were greatest in the first 30 days after infection but remained higher than controls even after this period.
5/n
5/n
12:22 PM - Apr 10, 2023
In response to Aviral Vatsa.
Results showed that non-hospitalized cases had an increased risk of incident VTE and death. Individuals with primary COVID-19 hospitalization had an increased risk of all outcomes considered, with the largest effect sizes being with VTE, heart failure, and stroke.
4/n
4/n
12:21 PM - Apr 10, 2023
In response to Aviral Vatsa.
The study included the following incident outcomes: myocardial infarction, stroke, heart failure, atrial fibrillation, venous thromboembolism (VTE), pericarditis, all-cause death, cardiovascular death, and IHD death.
3/n
3/n
12:21 PM - Apr 10, 2023
In response to Aviral Vatsa.
Each COVID-19 case was propensity score-matched to two uninfected controls on age, sex, deprivation, body mass index, ethnicity, diabetes, prevalent ischemic heart disease, smoking, hypertension, and high cholesterol.
2/n
2/n
12:21 PM - Apr 10, 2023
In response to Elizabeth Murray.
Let the govt support doctors with resources to fight disinformation. Doing it in our own time and with own resources takes a toll at multiple levels. Happy to do it, but a systematic approach will surely he more efficient.
Govt should put the money where the evidence is.
Govt should put the money where the evidence is.
02:01 PM - Apr 03, 2023
In response to Melissa Griffith ☕ aka Masker.
Thanks for sharing.
Indeed that's not an uncommon challenge. A lot is being talked about graded, paced, rationing energy, being able to take adequate rest... Not sure why NIH would miss all that.
Indeed that's not an uncommon challenge. A lot is being talked about graded, paced, rationing energy, being able to take adequate rest... Not sure why NIH would miss all that.
06:40 AM - Apr 02, 2023
In response to Salma Typhii.
A difference however is that this virus impacts almost all systems of the body and not just respiratory.
03:26 PM - Mar 25, 2023
In response to Aviral Vatsa.
7. End Organ Damage -
"Primary outcome was prevalence of single- and multi-organ impairment at 6 and 12 months post COVID-19."
https://journals.sagepub.c...
"Primary outcome was prevalence of single- and multi-organ impairment at 6 and 12 months post COVID-19."
https://journals.sagepub.c...
11:50 AM - Mar 25, 2023
In response to Aviral Vatsa.
6. Viral reactivation - of previously residing viruses in the body.
"These findings suggest that many long COVID symptoms may not be a direct result of the SARS-CoV-2 virus but may be the result of COVID-19 inflammation-induced EBV reactivation."
https://www.mdpi.com/2076-...
"These findings suggest that many long COVID symptoms may not be a direct result of the SARS-CoV-2 virus but may be the result of COVID-19 inflammation-induced EBV reactivation."
https://www.mdpi.com/2076-...
mdpi.com
Pathogens | Free Full-Text | Investigation of Long COVID Prevalence and Its Relationship to Epstein-Barr Virus Reactivation
Coronavirus disease 2019 (COVID-19) patients sometimes experience long-term symptoms following resolution of acute disease, including fatigue, brain fog, and rashes. Collectively these have become known as long COVID. Our aim was to first determine long COVID prevalence in 185 randomly surveyed COVI..
11:48 AM - Mar 25, 2023
In response to Aviral Vatsa.
4. Viral Debris , Viral persistence -
Parts of virus and/or the virus continues to be present months after the acute infection.
'Our data indicate that in some patients SARS-CoV-2 can cause systemic infection and persist in the body for months."
https://www.nature.com/art...
Parts of virus and/or the virus continues to be present months after the acute infection.
'Our data indicate that in some patients SARS-CoV-2 can cause systemic infection and persist in the body for months."
https://www.nature.com/art...
nature.com
SARS-CoV-2 infection and persistence in the human body and brain at autopsy | Nature
Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction1–3 during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with some patients experiencing prolonged symptoms, termed post-acute sequelae of SARS-CoV-2 (refs. 4,5). However, th..
11:45 AM - Mar 25, 2023
In response to Aviral Vatsa.
4. Micro clots -
"Fibrin amyloid microclots that block capillaries and inhibit the transport of O2 to tissues, accompanied by platelet hyperactivation, provide a ready explanation for the symptoms of Long COVID/PASC."
scholar.google.com/scholar_lookup…
"Fibrin amyloid microclots that block capillaries and inhibit the transport of O2 to tissues, accompanied by platelet hyperactivation, provide a ready explanation for the symptoms of Long COVID/PASC."
scholar.google.com/scholar_lookup…
11:44 AM - Mar 25, 2023
In response to Aviral Vatsa.
3. Auto-Immune disease after COVID -
"In conclusion, our preliminary data suggest that COVID-19 is associated with a significantly different risk of various autoimmune diseases".
https://www.thelancet.com/...
"In conclusion, our preliminary data suggest that COVID-19 is associated with a significantly different risk of various autoimmune diseases".
https://www.thelancet.com/...
thelancet.com
Risk of autoimmune diseases in patients with COVID-19: a retrospective cohort study - eClinicalMedicine
COVID-19 is associated with a different degree of risk for various autoimmune diseases. Given the large sample size and relatively modest effects these findings should be replicated in an independent dataset. Further research is needed to better understand the underlying mechanisms.
11:43 AM - Mar 25, 2023
In response to Aviral Vatsa.
2. Immune dysregulation-
"Patients with LC had highly activated innate immune cells, lacked naive T and B cells and showed elevated expression of type I IFN (IFN-β) and type III IFN (IFN-λ1) that remained persistently high at 8 months after infection."
https://t.co/xqGUJ2W7I0
"Patients with LC had highly activated innate immune cells, lacked naive T and B cells and showed elevated expression of type I IFN (IFN-β) and type III IFN (IFN-λ1) that remained persistently high at 8 months after infection."
https://t.co/xqGUJ2W7I0
t.co
Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection | Nature Immunology
A proportion of patients surviving acute coronavirus disease 2019 (COVID-19) infection develop post-acute COVID syndrome (long COVID (LC)) lasting longer than 12 weeks. Here, we studied individuals with LC compared to age- and gender-matched recovered individuals without LC, unexposed donors and ind..
11:41 AM - Mar 25, 2023
