Cedric Graebin
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Are you ready for this Friday's sermon?

https://open.spotify.com/t...
09:58 AM - Jun 30, 2023
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Cedric Graebin
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For today's #SpoutibleMusic , here's Andrew Bird's NPR Tiny Desk sessions from 2016. One of my favourites from the series:

https://www.youtube.com/wa...
Andrew Bird: NPR Music Tiny Desk Concert - YouTube

May 31, 2016 by BOB BOILEN • It's been a joy to hear the music of Andrew Bird shift and change. Bird's early music, from the late '90s, was steeped in hot ja...

06:02 AM - Jun 26, 2023
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Christopher Bouzy
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thread 1 Threaded Spouts
It seems some of you are bringing your bad habits from Twitter here, so let me make this clear. If you are part of a group targeting others here for any reason, we will remove your account. If you have an issue with someone else, use the block button.
07:20 PM - Jun 20, 2023
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Cedric Graebin
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My homeland elected a centre-left president and voted for far right, money-grabbing, lust-for-power evangelicals and "defenders of the family values" representatives in the Congress and Senate. This is not going to end well.
Mac Margolis @macmargolis
Brazil's challenge is not just to thwart environmental criminals and the flow of dirty money that enables them. The Lula government must also navigate a more hostile, predatory political class that holds forests ransom to pork and patronage. W/
robmuggah https://t.co/lBYibReRGj
03:46 PM - Jun 18, 2023
05:26 AM - Jun 19, 2023
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Derek Lowe
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Will reducing Tau protein be a therapy for Alzheimer’s? We’ve never been sure, but we might be about to find out:
https://www.science.org/co...
03:51 PM - Jun 12, 2023
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Derek Lowe
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What does ketamine do for depression, and how does it do it? Puzzling new evidence:
https://www.science.org/co...
02:44 PM - May 31, 2023
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Compound Interest
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It's #NationalNailPolishDay – here's a look at the polymers, plasticisers and pigments that give nail polish its colour and sheen: https://www.compoundchem.c...
03:39 AM - Jun 01, 2023
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Cedric Graebin
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Yesterday, while I was donating blood as a part of the NHS Scotland Blood drive (please donate if you can!), I heard this wisdom from one of the attending nurses:

"I tend to say yes to nearly everything. If you say 'no', nothing changes."

Been thinking about it since.
03:30 AM - May 31, 2023
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Derek Lowe
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Did a famous early synthesis of a chain-linked “catenane” compound actually work back in 1960, or was it wishful thinking.

Now we (and the 93-year-old author!) know:

https://www.science.org/co...
04:48 PM - May 30, 2023
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Bernice A. King
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Goodnight, Queen. #TinaTurner #SimplytheBest
03:05 PM - May 24, 2023
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Cedric Graebin
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A week with a new Blur song is always a good week - https://www.youtube.com/wa...

#SpoutibleMusic #MusicMonday
Blur - The Narcissist (Official Visualiser) - YouTube

Blur - The Narcissist (Visualiser) Listen now: http://blur.lnk.to/thenarcissistThe Narcissist - the first single taken from the new album ‘The Ballad Of Darr...

05:53 AM - May 22, 2023
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Cedric Graebin
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Carrot chemistry - or using carrots to perform chemical reactions! And, as it seems, this carrot-based reactor (from people working at AbbVie) works quite nicely for the reduction of ketones!

https://doi.org/10.1021/ac...
07:07 AM - May 17, 2023
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Cedric Graebin
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Today was my first day cycling to work.
My commute time was reduced from 30-36 min (either walking on or the bus to a 15 minute ride.
I got tired but it felt good riding on a bike again.
03:42 AM - May 17, 2023 (Edited)
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Cedric Graebin
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thread 2 Threaded Spouts
Rita Lee was a giant. It will be sorely missed.

https://www.nytimes.com/20...
06:30 AM - May 11, 2023
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Cedric Graebin
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So Kitara Ravache from Niterói was arrested then?
A. J. Woodson @MrAJWoodson
Live Updates: George Santos Is in Custody Facing Federal Charges #GeorgeSantos #santos #ResignSantos #Congressman
09:33 AM - May 10, 2023
09:40 AM - May 10, 2023
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Derek Lowe
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“Molecular glues” are a hot field of research, but we’re only beginning to figure out how they work at all:
https://www.science.org/co...
03:00 PM - May 04, 2023
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Cedric Graebin
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Let me ask the spoutible crowd a question: would you find useful if I wrote long-form (newsletter) texts about the tiny field of science I'm in? (mostly design and development of new drugs, new discoveries in the field, science oddities)
03:32 AM - May 03, 2023
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Derek Lowe
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The EPA is ready to ban a widely used solvent, but many chemists (and many entire industries) aren’t sure if that can work:

https://www.science.org/co...
09:55 AM - May 02, 2023
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Christopher Bouzy
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Threads will be live next week, and the app will be soon to follow.
09:06 PM - Apr 27, 2023
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Cedric Graebin
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#SpoutingClassics - "Days", a classic song by the band Television, on a very good cover made by the guys from Real Estate

https://open.spotify.com/t...
10:38 AM - Apr 27, 2023
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Derek Lowe
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Have you heard of resveratrol? About sirtuins and the association with longevity?

Have you heard that none of that is true?
https://www.science.org/co...
03:10 PM - Apr 20, 2023
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Cedric Graebin
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Looks like Spotify is down, or down-ish?
10:17 AM - Apr 19, 2023
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Derek Lowe
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Ozempic and the other drugs of its class might be doing more than people realize - a lot more:
https://www.science.org/co...
02:38 PM - Apr 17, 2023
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Compound Interest
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Happy #Easter to those of you celebrating! Here's a look at a selection of substances that can be used to dye eggshells in C&EN: https://cen.acs.org/articl...
04:42 AM - Apr 09, 2023
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Derek Lowe
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How much chemistry has ChatGPT been exposed to? How much does it understand? The answer to the second question is “zero”:
https://www.science.org/co...
02:46 PM - Apr 04, 2023
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Cedric Graebin
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Some music for this Tuesday:
"Not Strong Enough" by the trio boygenius

https://www.youtube.com/wa...
boygenius – Not Strong Enough (official music video) - YouTube

boygenius – Not Strong Enough (official music video) listen to “Not Strong Enough”: https://boygenius.lnk.to/notstrongenoughpre-order “the record” out march ...

07:15 AM - Apr 04, 2023
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Cedric Graebin
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In response to Creative AF (She/Her).
You know, for the past 20 years there has been some people trying to change this:
- the Doctors Without Borders MSF Access campaign
- Drugs for Neglected Diseases initiative (DNDi)
- Medicines for Malaria Venture (MMV)

(disclaimer: I work on a MMV-funded project, so I might be biased)
11:44 AM - Mar 31, 2023
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Cedric Graebin
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In response to Kathleen Rupnow.
Hi Kathleen! - There are some new drugs on clinical trials for the disease trying to be more than symptom alleviating agents - https://content.iospress.c...
11:36 AM - Mar 31, 2023
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Cedric Graebin
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In response to Tina Tague.
1) I am so sorry. I have someone close to me who has it and it is a drag.
2) It doesn't seem to be some that would be a breakthrough on the horizon, mostly improvements on current therapies - https://www.ncbi.nlm.nih.g...
3) It seems that some cognitive therapies and acupu
11:24 AM - Mar 31, 2023
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