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Thread: Collated Over-The-Counter Products for mitigating SARS-COV-2 based on published studies. (Work in progress) Haven't included mouthwashes or sinus washes - just didnt think of them until afterwards
08:05 AM - Aug 28, 2023
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thread 2/40
Nasal spray with Iota-Carrageenan - Efficacious against the virus itself - (2021) https://www.ncbi.nlm.nih.g...
08:06 AM - Aug 28, 2023
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thread 3/40
Quercetin – Probably efficacious against the virus itself (2022) https://onlinelibrary.wile...
08:07 AM - Aug 28, 2023
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thread 4/40
EGCG - Probably efficacious against the virus itself (2022) https://www.ncbi.nlm.nih.g...
08:08 AM - Aug 28, 2023
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thread 5/40
Lactoferrin – Possibly efficacious against the virus itself (2021) https://www.ncbi.nlm.nih.g...
08:09 AM - Aug 28, 2023
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thread 6/40
Nattokinase - Probably efficacious against the virus itself (2022) https://www.ncbi.nlm.nih.g...
08:11 AM - Aug 28, 2023
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BromAc -Bromelain and Acetylcysteine (and therefore possibly NAC?) – In theory efficacious against the virus itself (2021) https://www.ncbi.nlm.nih.g...
08:12 AM - Aug 28, 2023
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thread 8/40
UDCA / TUDCA – In theory efficacious
in silico (simulation) & In vitro (outside of a living organism) study 2020 https://www.ncbi.nlm.nih.g...
Non Clinical https://theconversation.co...
08:14 AM - Aug 28, 2023
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Metformin (and therefore possibly Berberine?) - Probably effective against Long COVID 2023 https://www.thelancet.com/...
08:15 AM - Aug 28, 2023
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thread 10/40
Antihistamines / Cetirizine - Probably effective against Long COVID 2023 https://www.ncbi.nlm.nih.g...
08:15 AM - Aug 28, 2023
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thread 11/40
Vitamin D3 - Probably effective against Long COVID 2022 Meta https://www.ncbi.nlm.nih.g...
08:16 AM - Aug 28, 2023
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thread 12/40
Zinc - Probably effective against Long COVID 2022 https://pubmed.ncbi.nlm.ni...
08:17 AM - Aug 28, 2023
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thread 13/40
Famotidine - Probably effective against Long COVID 2022 https://gut.bmj.com/conten...
08:19 AM - Aug 28, 2023
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thread 14/40
Astaxanthin - Possibly effective against Long COVID 2021 https://www.ncbi.nlm.nih.g...
08:20 AM - Aug 28, 2023
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thread 15/40
* Nigella Sativa / Black Seed Oil / Thymoquinone - NOTED ONLY - Note this Traditional Islamic Medicine has a special significance in Islam - 2021 study https://pubmed.ncbi.nlm.ni...
08:20 AM - Aug 28, 2023
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thread 16/40
* Olive leaf Extract - NOTED ONLY - Olive tree products had traditionally been used in the Mediterranean region for medicinal purposes. Trial 2021, published 2022 https://www.ncbi.nlm.nih.g...
08:21 AM - Aug 28, 2023
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thread 17/40
* Traditional Chinese Medicines - Noted – There are a number of TCMs that are under investigation – TCM requires individual examination and assessment and in reality doesn't dispose well to buying OTC / Off the shelf supplements which could cause imbalances in the body
08:22 AM - Aug 28, 2023
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thread 18/40
* Nitric Oxide Nasal Spray 1 - Noted with issues - Study sponsored by SaNOtize Research & Development Corporation . 2021 https://www.ncbi.nlm.nih.g...
08:22 AM - Aug 28, 2023
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thread 19/40
* Nitric Oxide Nasal Spray 2 “The significant reduction in SARS-CoV-2 ... in this study support the use of NONS for treatment of COVID-19 patients in those at risk of illness progression.” 2022 https://www.thelancet.com/...
08:23 AM - Aug 28, 2023
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thread 20/40
* Xylitol / GSE Nose Spray - Noted with issues - Initial Study sponsored by Xlear, Inc – “grapefruit seed extract and xylitol significantly eliminates SARS-CoV-2”. 2020 Limited study 2020 https://www.ncbi.nlm.nih.g...
08:24 AM - Aug 28, 2023
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thread 21/40
* PycnogenolⓇ - Noted with issues – (Franziska Weichmann is an employee of Horphag Research LTD.) 2020 https://www.ncbi.nlm.nih.g...
08:24 AM - Aug 28, 2023
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thread 22/40
Bovine Colustrum - Noted with issues – Studies seem to be using SARS COV2 injected into Calving females in order to generate antibodies for human use. 2022 https://pubmed.ncbi.nlm.ni...
08:25 AM - Aug 28, 2023
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thread 23/40
Omega 3 Supplements - Noted - Useful as part of a healthy diet which may lead to better outcomes from Acute SARS and Long COVID but not directly involved in mechanisms of fighting the virus itself or LC symptoms. 2022 https://www.ncbi.nlm.nih.g...
08:26 AM - Aug 28, 2023
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Garlic / Allicin - Noted - Currently ineffective - in vitro studies 2021 https://www.frontiersin.or...
08:27 AM - Aug 28, 2023
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thread 25/40
CPC Mouthwashes - Efficacious against the SARS virus - Meta of Studies 2023 (In vivo “within the living.” It refers to work that's performed in a whole, living organism) may cause mouth irritation & temp staining of the teeth or tongue https://onlinelibrary.wile...
08:28 AM - Aug 28, 2023
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thread 26/40
EGCG - Previfenon® Seems to be the furthest developed EGCG based therapy study to interrupt SARS at the ACE 2 Receptor

Bearing in mind it's just EGCG from Green Tea to some extent and follows on from a previous study from 2020 which had promising results https://www.melisainstitut...
08:30 AM - Aug 28, 2023
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08:31 AM - Aug 28, 2023
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thread 28/40
08:31 AM - Aug 28, 2023
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Artemesia / Wormwood - NOTED - No evidence, only a suggested possibility as a therapy https://www.ncbi.nlm.nih.g...
08:32 AM - Aug 28, 2023
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thread 30/40
08:33 AM - Aug 28, 2023
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thread 31/40
Dandelion Root - Efficacious In Theory - In Vitro Study showed good results against the virus itself but requires further practical studies to confirm. https://www.mdpi.com/1424-...
08:34 AM - Aug 28, 2023
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thread 32/40
Propolis Propomax® capsules produced with dehydrated standardized Brazilian green propolis extract, EPP-AF® - NOTED - Trial underway https://trialsjournal.biom...
08:35 AM - Aug 28, 2023
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thread 33/40
Bee Propolis - Efficacious in theory - Propolis components, including CAPE, rutin, quercetin, kaempferol and myricetin have demonstrated in silico a strong interaction with ACE2. Kaempferol reduced the expression of TMPRSS2 https://www.sciencedirect....
08:36 AM - Aug 28, 2023
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thread 34/40
L Lysine supplements - Efficacious in theory.
Personal anecdotal: may help with COVID Brain fog. I titrated up to Elvanse 50mg at the same time as I caught COVID last year and it alleviated my brain fog almost immediately https://www.ncbi.nlm.nih.g...
08:36 AM - Aug 28, 2023
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thread 35/40
Ubiquinol - Not Proven Efficacious (2023 - placebo-controlled, double-blind) https://www.thelancet.com/...
08:37 AM - Aug 28, 2023
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thread 36/40
Curcumin **Specifically HydroCurc** POSSIBLY efficacious for Long COVID imflammation relief. Results for one specfic formultion MAY NOT apply in general.
- other studies have not found Curcumin to be as successful as a ACE 2 Receptor as EGCG or Quercetin https://www.mdpi.com/2072-...
08:38 AM - Aug 28, 2023
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Study sponsored by owners of the formulation but study did not declare Conlict of Interest
Reference: Gencor pacific / HydroCurc https://www.gencorpacific....
08:39 AM - Aug 28, 2023
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thread 38/40
Not OTC but added for context:
Tixagevimab and Cilgavimab (Evusheld) for Pre-Exposure Prophylaxis of COVID-19 (JAMA. 2022)
Monoclonal antibodies to be administered concomitantly by **intramuscular injection** for preexposure prophylaxis
https://jamanetwork.com/jo...
08:41 AM - Aug 28, 2023
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thread 39/40
UPDATE: Lactoferrin - NOT PROVEN efficacious in HOSPITALISED patients - further studies required specifically as PrEP (March 2023) https://www.ncbi.nlm.nih.g...
08:42 AM - Aug 28, 2023
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thread 40/40
NAC - not proven efficacious

NAC should be taken with Glycine to aid the reaction but I don't think that was relevant to these results. https://openres.ersjournal...
08:43 AM - Aug 28, 2023
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