Trish Greenhalgh
A
1. Thread on masks (also posted on Twitter). Addresses:
- Why so much controversy?
- Airborne transmission
- RCTs of masks – strengths/limitations, community, healthcare settings
- Meta-analyses – gold standard or lazy lumping?
- Non-RCT evidence – why is it needed, what does it show?
- AOB
09:16 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
2. Before I start, here’s my OLD mask thread from Twitter July 21, which ran to >100 tweets. Some of that is now rather dated but a lot still holds. I’ll paste the best from that into this new thread. Will take a while (~100 total)
https://twitter.com/trishg...
09:17 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
3. WHY IS MASKING SO CONTROVERSIAL?
First, ‘masks’ and ‘masking’ are very broad terms. They cover different technologies (cloth, medical, respirator), wearers (public, patient, healthcare worker), settings (low v high risk) and requirements (mandated v free choice).
09:18 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
4. WHY CONTROVERSIAL?
Because of this multiplicity, statements like “masks [don’t] work” may be referring to very different interventions in different populations for different activities at different times, not to mention different diseases. The literature, in short, is a mess.
09:18 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
5. WHY CONTROVERSIAL?
Second, masking is a cultural practice as well as a public health intervention. It has symbolic meaning. Pirates and burglars wear masks. To some, masking means you’re a ‘pansy’, ‘sheep’ etc. Masking offends libertarians.
https://www.bmj.com/conten...
09:19 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
6. WHY CONTROVERSIAL?
There’s strong social pressure to mask in some settings to contribute to the greater good (“my mask protects you”). People may feel pushed into doing something which a) feels awkward, b) symbolises an allegiance they don’t identify with and c) they feel is ineffective.
09:20 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
7. WHY CONTROVERSIAL?
Third, masking (whatever its benefits) has some downsides. It’s (depending on the design) uncomfortable. It can interfere with communication (especially if hard of hearing). If you work long shifts, it gets hot/sweaty behind the mask.
https://www.bmj.com/conten...
09:20 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
8. WHY CONTROVERSIAL?
In short, masking is something many of us feel strongly about. It’s not even possible to separate “the science” of masks from “the politics”, since science does not sit in some protected bubble away from the rest of society. Read on!
09:21 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
9. AIRBORNE TRANSMISSION
Understanding why & to what extent masks work requires knowledge of how the SARS-CoV-2 virus is transmitted. With colleagues, I published this summary of evidence that it spreads *predominantly* via air. https://twitter.com/trishg...
09:22 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
10. AIRBORNE TRANSMISSION
I responded to critics of that paper here https://twitter.com/trishg... (plus see more in thread below).
09:22 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
11. AIRBORNE TRANSMISSION
For those who want depth and detail, here’s Chia Wang and team’s stunning review of the evidence for airborne transmission in Science (one of the very top scientific journals).
https://www.science.org/do...
09:23 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
12. AIRBORNE TRANSMISSION
In sum, it is *settled science* that SARS-CoV-2 is transmitted via the air. Settled, that is, in all branches of science *except* key groups of doctors, including some in powerful positions at the World Health Organisation. I’ll return to that paradox later.
09:23 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
13. AIRBORNE TRANSMISSION
Medical/surgical (~same thing) masks are designed to stop spatter (e.g. your dentist dribbling into your mouth). Most aren’t made to a specific quality standard. Respirators are designed to filter out airborne particles. They ARE made to a standard.
09:23 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
14. AIRBORNE TRANSMISSION
If SARS-CoV-2 were spread mainly by droplets, we’d need to focus on handwashing and medical/surgical masks which stop wet drops. If mainly via the air, we need to focus on air quality and use the kind of face coverings that stop airborne particles (i.e. respirators).
09:23 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
15. AIRBORNE TRANSMISSION
All masks stop some airborne particles (even if the holes are bigger than the particles, fibres are criss-crossed and electrostatic forces kick in). But N95 (FFP2) respirators stop >95% of particles of SARS-CoV-2 size, and N99s (FFP3s) stop >99%.
09:24 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
16. AIRBORNE TRANSMISSION
A year ago, we wrote this article recommending that everyone upgrades their mask from either medical/surgical to respirator.
https://theconversation.co...
09:24 AM - Feb 26, 2023
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Trish Greenhalgh
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17. AIRBORNE TRANSMISSION
Whilst respirators protect best, ANY mask is better than none. Efficiency at reducing transmission of respiratory aerosol:
N95 respirator 99%
Medical mask 59%
Bandana (single) 47% (double) 60%
Face shield 2%
https://tandfonline.com/do...
In response to Trish Greenhalgh.
09:25 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
18. AIRBORNE TRANSMISSION
The above, a laboratory study of artificial aerosols, should not be taken as direct evidence that these masks would be this effective/ineffective in preventing real-world SARS-CoV-2 transmission. But they *add to the mix of evidence*. More on that later.
09:26 AM - Feb 26, 2023
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Trish Greenhalgh
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In response to Trish Greenhalgh.
19. AIRBORNE TRANSMISSION
Face shields are only 2% effective cos they’re designed to stop spatter, NOT filter air. Medical masks don’t fit snugly, so instead of breathing filtered air, you breathe what leaks in round the sides. This is why a doubled-over bandana works pretty well!
09:26 AM - Feb 26, 2023
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