Aviral Vatsa
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Thread.
1. Some of the ways how SARS Cov2 is affecting us as Long COVID (LC):
- Immune dysregulation
- Auto immune disease
- micro clots
- viral debris
- persistence of SARS virus
- Viral reactivation- e.g. EBV, CMV
- end organ damage

It is one of the worst viruses to impact us. Stay safe
11:40 AM - Mar 25, 2023
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Aviral Vatsa
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2. Immune dysregulation-

"Patients with LC had highly activated innate immune cells, lacked naive T and B cells and showed elevated expression of type I IFN (IFN-β) and type III IFN (IFN-λ1) that remained persistently high at 8 months after infection."

https://t.co/xqGUJ2W7I0
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11:41 AM - Mar 25, 2023
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3. Auto-Immune disease after COVID -
"In conclusion, our preliminary data suggest that COVID-19 is associated with a significantly different risk of various autoimmune diseases".

https://www.thelancet.com/...
11:43 AM - Mar 25, 2023
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4. Micro clots -
"Fibrin amyloid microclots that block capillaries and inhibit the transport of O2 to tissues, accompanied by platelet hyperactivation, provide a ready explanation for the symptoms of Long COVID/PASC."

scholar.google.com/scholar_lookup…
11:44 AM - Mar 25, 2023
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4. Viral Debris , Viral persistence -
Parts of virus and/or the virus continues to be present months after the acute infection.

'Our data indicate that in some patients SARS-CoV-2 can cause systemic infection and persist in the body for months."

https://www.nature.com/art...
11:45 AM - Mar 25, 2023
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